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Presence of unique glyoxalase III proteins in plants indicates the existence of shorter route for methylglyoxal detoxification

Glyoxalase pathway, comprising glyoxalase I (GLY I) and glyoxalase II (GLY II) enzymes, is the major pathway for detoxification of methylglyoxal (MG) into D-lactate involving reduced glutathione (GSH). However, in bacteria, glyoxalase III (GLY III) with DJ-1/PfpI domain(s) can do the same conversion...

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Detalles Bibliográficos
Autores principales: Ghosh, Ajit, Kushwaha, Hemant R, Hasan, Mohammad R, Pareek, Ashwani, Sopory, Sudhir K, Singla-Pareek, Sneh L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702089/
https://www.ncbi.nlm.nih.gov/pubmed/26732528
http://dx.doi.org/10.1038/srep18358