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SPECT/NIRF Dual Modality Imaging for Detection of Intraperitoneal Colon Tumor with an Avidin/Biotin Pretargeting System

We describe herein dual-modality imaging of intraperitoneal colon tumor using an avidin/biotin pretargeting system. A novel dual-modality probe, (99m)Tc-HYNIC-lys(Cy5.5)-PEG(4)-biotin, was designed, synthesized and characterized. Single-photon emission computed tomography/ computed tomography (SPECT...

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Detalles Bibliográficos
Autores principales: Dong, Chengyan, Yang, Sujuan, Shi, Jiyun, Zhao, Huiyun, Zhong, Lijun, Liu, Zhaofei, Jia, Bing, Wang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702112/
https://www.ncbi.nlm.nih.gov/pubmed/26732543
http://dx.doi.org/10.1038/srep18905