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Next-Generation Bacillus anthracis Live Attenuated Spore Vaccine Based on the htrA(-) (High Temperature Requirement A) Sterne Strain

Anthrax is a lethal disease caused by the gram-positive spore-producing bacterium Bacillus anthracis. Live attenuated vaccines, such as the nonencapsulated Sterne strain, do not meet the safety standards mandated for human use in the Western world and are approved for veterinary purposes only. Here...

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Detalles Bibliográficos
Autores principales: Chitlaru, Theodor, Israeli, Ma’ayan, Bar-Haim, Erez, Elia, Uri, Rotem, Shahar, Ehrlich, Sharon, Cohen, Ofer, Shafferman, Avigdor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702213/
https://www.ncbi.nlm.nih.gov/pubmed/26732659
http://dx.doi.org/10.1038/srep18908