Identification and classification of small molecule kinases: insights into substrate recognition and specificity

BACKGROUND: Many prokaryotic kinases that phosphorylate small molecule substrates, such as antibiotics, lipids and sugars, are evolutionarily related to Eukaryotic Protein Kinases (EPKs). These Eukaryotic-Like Kinases (ELKs) share the same overall structural fold as EPKs, but differ in their modes o...

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Detalles Bibliográficos
Autores principales: Oruganty, Krishnadev, Talevich, Eric E., Neuwald, Andrew F., Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702295/
https://www.ncbi.nlm.nih.gov/pubmed/26738562
http://dx.doi.org/10.1186/s12862-015-0576-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702295/
https://www.ncbi.nlm.nih.gov/pubmed/26738562
http://dx.doi.org/10.1186/s12862-015-0576-x

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