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Identification and classification of small molecule kinases: insights into substrate recognition and specificity

BACKGROUND: Many prokaryotic kinases that phosphorylate small molecule substrates, such as antibiotics, lipids and sugars, are evolutionarily related to Eukaryotic Protein Kinases (EPKs). These Eukaryotic-Like Kinases (ELKs) share the same overall structural fold as EPKs, but differ in their modes o...

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Detalles Bibliográficos
Autores principales:	Oruganty, Krishnadev, Talevich, Eric E., Neuwald, Andrew F., Kannan, Natarajan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702295/ https://www.ncbi.nlm.nih.gov/pubmed/26738562 http://dx.doi.org/10.1186/s12862-015-0576-x

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