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Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster

BACKGROUND: A generally accepted approach to the analysis of RNA-Seq read count data does not yet exist. We sequenced the mRNA of 726 individuals from the Drosophila Genetic Reference Panel in order to quantify differences in gene expression among single flies. One of our experimental goals was to i...

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Detalles Bibliográficos
Autores principales: Lin, Yanzhu, Golovnina, Kseniya, Chen, Zhen-Xia, Lee, Hang Noh, Negron, Yazmin L. Serrano, Sultana, Hina, Oliver, Brian, Harbison, Susan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702322/
https://www.ncbi.nlm.nih.gov/pubmed/26732976
http://dx.doi.org/10.1186/s12864-015-2353-z