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Monoallelic and biallelic deletions of 13q14 in a group of CLL/SLL patients investigated by CGH Haematological Cancer and SNP array (8x60K)

BACKGROUND: Deletion of 13q14 is the most common cytogenetic change in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and is detected in about 50 % of patients by fluorescence in situ hybridization (FISH), which can reveal presence of del(13)(q14) and mono- or biallelic deletion s...

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Detalles Bibliográficos
Autores principales: Grygalewicz, Beata, Woroniecka, Renata, Rygier, Jolanta, Borkowska, Klaudia, Rzepecka, Iwona, Łukasik, Martyna, Budziłowska, Agnieszka, Rymkiewicz, Grzegorz, Błachnio, Katarzyna, Nowakowska, Beata, Bartnik, Magdalena, Gos, Monika, Pieńkowska-Grela, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702365/
https://www.ncbi.nlm.nih.gov/pubmed/26740820
http://dx.doi.org/10.1186/s13039-015-0212-x