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Intranasal Human Growth Hormone (hGH) Induces IGF-1 Levels Comparable With Subcutaneous Injection With Lower Systemic Exposure to hGH in Healthy Volunteers

CONTEXT: The development of an improved, efficacious human GH (hGH) product administered by a noninjectable route of delivery such as the nasal route is highly desirable. We have developed a novel nasal hGH product (CP024) that showed excellent nasal absorption in animal models; however, the transla...

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Detalles Bibliográficos
Autores principales: Lewis, Andrew L., Jordan, Faron, Patel, Tina, Jeffery, Kirk, King, Gareth, Savage, Martin, Shalet, Stephen, Illum, Lisbeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702464/
https://www.ncbi.nlm.nih.gov/pubmed/26425883
http://dx.doi.org/10.1210/jc.2014-4146