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Oligomerization Requirements for MX2-Mediated Suppression of HIV-1 Infection

Human myxovirus resistance 2 (MX2/MXB) is an interferon-stimulated gene (ISG) and was recently identified as a late postentry suppressor of human immunodeficiency virus type 1 (HIV-1) infection, inhibiting the nuclear accumulation of viral cDNAs. Although the HIV-1 capsid (CA) protein is believed to...

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Detalles Bibliográficos
Autores principales: Dicks, Matthew D. J., Goujon, Caroline, Pollpeter, Darja, Betancor, Gilberto, Apolonia, Luis, Bergeron, Julien R. C., Malim, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702540/
https://www.ncbi.nlm.nih.gov/pubmed/26446602
http://dx.doi.org/10.1128/JVI.02247-15