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A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) DNA cytosine deaminases can be incorporated into progeny virions and inhibit lentiviral replication. On the other hand, viral infectivity factor (Vif) of lentiviruses antagonizes A3-mediated antiviral activities by degra...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Rokusuke, Izumi, Taisuke, Yamada, Eri, Nakano, Yusuke, Misawa, Naoko, Ren, Fengrong, Carpenter, Michael A., Ikeda, Terumasa, Münk, Carsten, Harris, Reuben S., Miyazawa, Takayuki, Koyanagi, Yoshio, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702554/
https://www.ncbi.nlm.nih.gov/pubmed/26491161
http://dx.doi.org/10.1128/JVI.02612-15