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dbSUPER: a database of super-enhancers in mouse and human genome

Super-enhancers are clusters of transcriptional enhancers that drive cell-type-specific gene expression and are crucial to cell identity. Many disease-associated sequence variations are enriched in super-enhancer regions of disease-relevant cell types. Thus, super-enhancers can be used as potential...

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Detalles Bibliográficos
Autores principales: Khan, Aziz, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702767/
https://www.ncbi.nlm.nih.gov/pubmed/26438538
http://dx.doi.org/10.1093/nar/gkv1002