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UET: a database of evolutionarily-predicted functional determinants of protein sequences that cluster as functional sites in protein structures

The structure and function of proteins underlie most aspects of biology and their mutational perturbations often cause disease. To identify the molecular determinants of function as well as targets for drugs, it is central to characterize the important residues and how they cluster to form functiona...

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Detalles Bibliográficos
Autores principales: Lua, Rhonald C., Wilson, Stephen J., Konecki, Daniel M., Wilkins, Angela D., Venner, Eric, Morgan, Daniel H., Lichtarge, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702906/
https://www.ncbi.nlm.nih.gov/pubmed/26590254
http://dx.doi.org/10.1093/nar/gkv1279