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UET: a database of evolutionarily-predicted functional determinants of protein sequences that cluster as functional sites in protein structures
The structure and function of proteins underlie most aspects of biology and their mutational perturbations often cause disease. To identify the molecular determinants of function as well as targets for drugs, it is central to characterize the important residues and how they cluster to form functiona...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702906/ https://www.ncbi.nlm.nih.gov/pubmed/26590254 http://dx.doi.org/10.1093/nar/gkv1279 |