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HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease
More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urgency of understanding the regulatory genome as a key component for translating genetic results into mechanistic insights a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702929/ https://www.ncbi.nlm.nih.gov/pubmed/26657631 http://dx.doi.org/10.1093/nar/gkv1340 |