Cargando…

HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urgency of understanding the regulatory genome as a key component for translating genetic results into mechanistic insights a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ward, Lucas D., Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702929/
https://www.ncbi.nlm.nih.gov/pubmed/26657631
http://dx.doi.org/10.1093/nar/gkv1340

Ejemplares similares