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A new technique for modeling neuronal connectivity using human pluripotent stem cells

Purpose: We describe a technique for independently differentiating neocortical and mesencephalic dopaminergic (mDA) neurons from a single human pluripotent stem cell (hPSC) line, and subsequently allowing the two cell types to interact and form connections. Methods: Dopaminergic and neocortical prog...

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Detalles Bibliográficos
Autores principales: Lee, Chun-Ting, Bendriem, Raphael M., Freed, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702948/
https://www.ncbi.nlm.nih.gov/pubmed/25835555
http://dx.doi.org/10.3233/RNN-140488