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RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA

MicroRNAs (miRNAs) integrate with Argonaut (Ago) to create the RNA-induced silencing complex, and regulate gene expression by silencing target mRNAs. RNA editing of miRNA may affect miRNA processing, assembly of the Ago complex and target mRNA binding. However, the function of edited miRNA, assemble...

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Detalles Bibliográficos
Autores principales: Cui, Yalei, Huang, Tianzhi, Zhang, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703055/
https://www.ncbi.nlm.nih.gov/pubmed/26674414
http://dx.doi.org/10.1098/rsob.150126