Cargando…

Dual functionality of O-GlcNAc transferase is required for Drosophila development

Post-translational modification of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc) catalysed by O-GlcNAc transferase (OGT) has been linked to regulation of diverse cellular functions. OGT possesses a C-terminal glycosyltransferase catalytic domain and N-terminal tetratricopeptide...

Descripción completa

Detalles Bibliográficos
Autores principales: Mariappa, Daniel, Zheng, Xiaowei, Schimpl, Marianne, Raimi, Olawale, Ferenbach, Andrew T., Müller, H.-Arno J., van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703063/
https://www.ncbi.nlm.nih.gov/pubmed/26674417
http://dx.doi.org/10.1098/rsob.150234