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Structural Examination of the Transient 3-Aminotyrosyl Radical on the PCET Pathway of E. coli Ribonucleotide Reductase by Multifrequency EPR Spectroscopy
[Image: see text] E. coli ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides, a process that requires long-range radical transfer over 35 Å from a tyrosyl radical (Y(122)•) within the β2 subunit to a cysteine residue (C(439)) within the α2 subunit. The radical...
Autores principales: | Seyedsayamdost, Mohammad R., Argirević, Tomislav, Minnihan, Ellen C., Stubbe, JoAnne, Bennati, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703294/ https://www.ncbi.nlm.nih.gov/pubmed/19821570 http://dx.doi.org/10.1021/ja903879w |
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