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NDRG2 Expression Decreases Tumor-Induced Osteoclast Differentiation by Down-regulating ICAM1 in Breast Cancer Cells

Bone matrix is properly maintained by osteoclasts and osteoblasts. In the tumor microenvironment, osteoclasts are increasingly differentiated by the various ligands and cytokines secreted from the metastasized cancer cells at the bone metastasis niche. The activated osteoclasts generate osteolytic l...

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Detalles Bibliográficos
Autores principales: Kim, Bomi, Nam, Sorim, Lim, Ji Hyun, Lim, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703347/
https://www.ncbi.nlm.nih.gov/pubmed/26759696
http://dx.doi.org/10.4062/biomolther.2015.105