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Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis
Extracellular bacteria, such as Pseudomonas aeruginosa and Klebsiella pneumoniae, have been reported to induce autophagy; however, the role and machinery of infection-induced autophagy remain elusive. We show that the pleiotropic Src kinase Lyn mediates phagocytosis and autophagosome maturation in a...
Hauptverfasser: | , , , , , , , , , , , , , |
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Format: | Online Artikel Text |
Sprache: | English |
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Public Library of Science
2016
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Schlagworte: | |
Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703367/ https://www.ncbi.nlm.nih.gov/pubmed/26735693 http://dx.doi.org/10.1371/journal.ppat.1005363 |