Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer

Identifying genes where a variant allele is preferentially expressed in tumors could lead to a better understanding of cancer biology and optimization of targeted therapy. However, tumor sample heterogeneity complicates standard approaches for detecting preferential allele expression. We therefore d...

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Detalles Bibliográficos
Autores principales: Halabi, Najeeb M., Martinez, Alejandra, Al-Farsi, Halema, Mery, Eliane, Puydenus, Laurence, Pujol, Pascal, Khalak, Hanif G., McLurcan, Cameron, Ferron, Gwenael, Querleu, Denis, Al-Azwani, Iman, Al-Dous, Eman, Mohamoud, Yasmin A., Malek, Joel A., Rafii, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703369/
https://www.ncbi.nlm.nih.gov/pubmed/26735499
http://dx.doi.org/10.1371/journal.pgen.1005755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703369/
https://www.ncbi.nlm.nih.gov/pubmed/26735499
http://dx.doi.org/10.1371/journal.pgen.1005755

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