Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression

Although hematopoietic stem cells (HSC) are the best-characterized and the most clinically used adult stem cells, efforts are still needed to understand how to best ex vivo expand these cells. Here we present our unexpected finding that OCT4 is involved in the enhancement of cytokine-induced expansi...

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Detalles Bibliográficos
Autores principales: Huang, Xinxin, Lee, Man-Ryul, Cooper, Scott, Hangoc, Giao, Hong, Ki-Sung, Chung, Hyung-Min, Broxmeyer, Hal E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703453/
https://www.ncbi.nlm.nih.gov/pubmed/26202933
http://dx.doi.org/10.1038/leu.2015.189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703453/
https://www.ncbi.nlm.nih.gov/pubmed/26202933
http://dx.doi.org/10.1038/leu.2015.189

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