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Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression
Although hematopoietic stem cells (HSC) are the best-characterized and the most clinically used adult stem cells, efforts are still needed to understand how to best ex vivo expand these cells. Here we present our unexpected finding that OCT4 is involved in the enhancement of cytokine-induced expansi...
Autores principales: | Huang, Xinxin, Lee, Man-Ryul, Cooper, Scott, Hangoc, Giao, Hong, Ki-Sung, Chung, Hyung-Min, Broxmeyer, Hal E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703453/ https://www.ncbi.nlm.nih.gov/pubmed/26202933 http://dx.doi.org/10.1038/leu.2015.189 |
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