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Transient hypoxia reprograms differentiating adipocytes for enhanced insulin sensitivity and triglyceride accumulation
OBJECTIVE: To investigate the impact of transient (2-4 h) hypoxia on metabolic reprogramming of adipocytes. METHODS: The impact of transient hypoxia on metabolic reprogramming was investigated in 3T3-L1 cells before and after differentiation. Glucose uptake, fatty acid oxidation, lipolysis, and mito...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703459/ https://www.ncbi.nlm.nih.gov/pubmed/26219415 http://dx.doi.org/10.1038/ijo.2015.137 |