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Cytoplasmic myosin exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability

The degree of chronic lymphocytic leukemia (CLL) B-cell antigen receptor (BCR) binding to myosin exposed apoptotic cells (MEACs) correlates with worse patient outcomes, suggesting a link to disease activity. Therefore, we studied MEAC formation and the effects of MEAC binding on CLL cells. In cell l...

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Detalles Bibliográficos
Autores principales: Cui, Xiaoxuan, Zhang, Lu, Magli, Amanda R., Catera, Rosa, Yan, Xiao-Jie, Griffin, Daniel O., Rothstein, Thomas L., Barrientos, Jacqueline, Kolitz, Jonathan E., Allen, Steven L., Rai, Kanti R., Chiorazzi, Nicholas, Chu, Charles C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703467/
https://www.ncbi.nlm.nih.gov/pubmed/26220042
http://dx.doi.org/10.1038/leu.2015.204