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Stabilization of zwitterionic versus canonical proline by water molecules

At physiological conditions, a majority of biomolecules (e.g., amino acids, peptides and proteins) exist predominantly in the zwitterionic form that usually decides the biological functions. However, zwitterionic amino acids are not geometrically stable in gas phase and this seriously hampers the un...

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Detalles Bibliográficos
Autores principales: Yang, Gang, Zhou, Lijun, Chen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703596/
https://www.ncbi.nlm.nih.gov/pubmed/26759758
http://dx.doi.org/10.1186/s40064-015-1661-8