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Muscle A-Kinase Anchoring Protein-α is an Injury-Specific Signaling Scaffold Required for Neurotrophic- and Cyclic Adenosine Monophosphate-Mediated Survival

Neurotrophic factor and cAMP-dependent signaling promote the survival and neurite outgrowth of retinal ganglion cells (RGCs) after injury. However, the mechanisms conferring neuroprotection and neuroregeneration downstream to these signals are unclear. We now reveal that the scaffold protein muscle...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Cameron, Evan G., Li, Jinliang, Stiles, Travis L., Kritzer, Michael D., Lodhavia, Rahul, Hertz, Jonathan, Nguyen, Tu, Kapiloff, Michael S., Goldberg, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703706/
https://www.ncbi.nlm.nih.gov/pubmed/26844267
http://dx.doi.org/10.1016/j.ebiom.2015.10.025