Cargando…

BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer

BCL9/9L proteins enhance the transcriptional output of the β-catenin/TCF transcriptional complex and contribute critically to upholding the high WNT signaling level required for stemness maintenance in the intestinal epithelium. Here we show that a BCL9/9L-dependent gene signature derived from indep...

Descripción completa

Detalles Bibliográficos
Autores principales: Moor, Andreas E., Anderle, Pascale, Cantù, Claudio, Rodriguez, Patrick, Wiedemann, Norbert, Baruthio, Frédérique, Deka, Jürgen, André, Sylvie, Valenta, Tomas, Moor, Matthias B., Győrffy, Balázs, Barras, David, Delorenzi, Mauro, Basler, Konrad, Aguet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703711/
https://www.ncbi.nlm.nih.gov/pubmed/26844272
http://dx.doi.org/10.1016/j.ebiom.2015.10.030