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BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer
BCL9/9L proteins enhance the transcriptional output of the β-catenin/TCF transcriptional complex and contribute critically to upholding the high WNT signaling level required for stemness maintenance in the intestinal epithelium. Here we show that a BCL9/9L-dependent gene signature derived from indep...
Autores principales: | Moor, Andreas E., Anderle, Pascale, Cantù, Claudio, Rodriguez, Patrick, Wiedemann, Norbert, Baruthio, Frédérique, Deka, Jürgen, André, Sylvie, Valenta, Tomas, Moor, Matthias B., Győrffy, Balázs, Barras, David, Delorenzi, Mauro, Basler, Konrad, Aguet, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703711/ https://www.ncbi.nlm.nih.gov/pubmed/26844272 http://dx.doi.org/10.1016/j.ebiom.2015.10.030 |
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