Collagen Specific T-Cell Repertoire and HLA-DR Alleles: Biomarkers of Active Refractory Rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and associates with HLA-DRB1*04. The Collagen IIp(261-273)-specific T cell repertoire in the peripheral blood of DR4 + patients at the onset of the disease shows a restricted TCR-beta chain usage among which the most frequent i...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Sante, Gabriele, Tolusso, Barbara, Fedele, Anna Laura, Gremese, Elisa, Alivernini, Stefano, Nicolò, Chiara, Ria, Francesco, Ferraccioli, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703746/
https://www.ncbi.nlm.nih.gov/pubmed/26844284
http://dx.doi.org/10.1016/j.ebiom.2015.11.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703746/
https://www.ncbi.nlm.nih.gov/pubmed/26844284
http://dx.doi.org/10.1016/j.ebiom.2015.11.019

Ejemplares similares