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Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects

BACKGROUND: Hyperglycemia-induced oxidative stress is one mechanism believed to underlie diabetic vascular disease. We tested the hypothesis that diabetic subjects heterozygous for extracellular superoxide dismutase (SOD3) R213G, which entails lower antioxidant capacity in tissues, have increased ri...

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Detalles Bibliográficos
Autores principales: Kobylecki, Camilla J., Afzal, Shoaib, Nordestgaard, Børge G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703764/
https://www.ncbi.nlm.nih.gov/pubmed/26844281
http://dx.doi.org/10.1016/j.ebiom.2015.11.026