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Embryonic transcription is controlled by maternally defined chromatin state

Histone-modifying enzymes are required for cell identity and lineage commitment, however little is known about the regulatory origins of the epigenome during embryonic development. Here we generate a comprehensive set of epigenome reference maps, which we use to determine the extent to which materna...

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Detalles Bibliográficos
Autores principales: Hontelez, Saartje, van Kruijsbergen, Ila, Georgiou, Georgios, van Heeringen, Simon J., Bogdanovic, Ozren, Lister, Ryan, Veenstra, Gert Jan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703837/
https://www.ncbi.nlm.nih.gov/pubmed/26679111
http://dx.doi.org/10.1038/ncomms10148