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Exclusive photorelease of signalling lipids at the plasma membrane

Photoactivation of caged biomolecules has become a powerful approach to study cellular signalling events. Here we report a method for anchoring and uncaging biomolecules exclusively at the outer leaflet of the plasma membrane by employing a photocleavable, sulfonated coumarin derivative. The novel c...

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Detalles Bibliográficos
Autores principales: Nadler, André, Yushchenko, Dmytro A., Müller, Rainer, Stein, Frank, Feng, Suihan, Mulle, Christophe, Carta, Mario, Schultz, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703838/
https://www.ncbi.nlm.nih.gov/pubmed/26686736
http://dx.doi.org/10.1038/ncomms10056