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A protective role for IL-13 receptor α 1 in bleomycin-induced pulmonary injury and repair

Molecular mechanisms that regulate lung repair vs. progressive scarring in pulmonary fibrosis remain elusive. Interleukin (IL)-4 and IL-13 are pro-fibrotic cytokines that share common receptor chains including IL-13 receptor (R) α1 and are key pharmacological targets in fibrotic diseases. However, t...

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Detalles Bibliográficos
Autores principales: Karo-Atar, D, Bordowitz, A, Wand, O, Pasmanik-Chor, M, Fernandez, I E, Itan, M, Frenkel, R, Herbert, D R, Finkelman, F D, Eickelberg, O, Munitz, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703942/
https://www.ncbi.nlm.nih.gov/pubmed/26153764
http://dx.doi.org/10.1038/mi.2015.56