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Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required for activity and regulation of erythrophagocytosis

Phagocytosis plays a key role in survival and pathogenicity of Entamoeba histolytica. We have recently demonstrated that an atypical kinase EhAK1 is involved in phagocytosis in this parasite. It is recruited to the phagocytic cups through interaction with EhCaBP1. EhAK1 manipulates actin dynamics by...

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Detalles Bibliográficos
Autores principales: Mansuri, M Shahid, Babuta, Mrigya, Ali, Mohammad Sabir, Bharadwaj, Ravi, jhingan, Gagan Deep, Gourinath, Samudrala, Bhattacharya, Sudha, Bhattacharya, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703981/
https://www.ncbi.nlm.nih.gov/pubmed/26739245
http://dx.doi.org/10.1038/srep16969