Functional inhibition of urea transporter UT-B enhances endothelial-dependent vasodilatation and lowers blood pressure via L-arginine-endothelial nitric oxide synthase-nitric oxide pathway

Mammalian urea transporters (UTs), UT-A and UT-B, are best known for their role in urine concentration. UT-B is especially distributed in multiple extrarenal tissues with abundant expression in vascular endothelium, but little is known about its role in vascular function. The present study investiga...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yi, Lau, Chi-Wai, Jia, Yingli, Li, Yingjie, Wang, Weiling, Ran, Jianhua, Li, Fei, Huang, Yu, Zhou, Hong, Yang, Baoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703984/
https://www.ncbi.nlm.nih.gov/pubmed/26739766
http://dx.doi.org/10.1038/srep18697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703984/
https://www.ncbi.nlm.nih.gov/pubmed/26739766
http://dx.doi.org/10.1038/srep18697

Ejemplares similares