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Ozone-induced IL-17A and neutrophilic airway inflammation is orchestrated by the caspase-1-IL-1 cascade

Ozone is a common environmental air pollutant leading to respiratory illness. The mechanisms regulating ozone-induced airway inflammation remain poorly understood. We hypothesize that ozone-triggered inflammasome activation and interleukin (IL)-1 production regulate neutrophilic airway inflammation...

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Detalles Bibliográficos
Autores principales: Che, Luanqing, Jin, Yan, Zhang, Chao, Lai, Tianwen, Zhou, Hongbin, Xia, Lixia, Tian, Baoping, Zhao, Yun, Liu, Juan, Wu, Yinfang, Wu, Yanping, Du, Jie, Li, Wen, Ying, Songmin, Chen, Zhihua, Shen, Huahao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703985/
https://www.ncbi.nlm.nih.gov/pubmed/26739627
http://dx.doi.org/10.1038/srep18680