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Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities

Aminotransferases of subfamily Iβ, which include histidinol phosphate aminotransferases (HspATs) and aromatic amino acid aminotransferases (ArATs), are structurally similar but possess distinct substrate specificities. This study, encompassing structural and biochemical characterisation of HspAT and...

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Detalles Bibliográficos
Autores principales: Nasir, Nazia, Anant, Avishek, Vyas, Rajan, Biswal, Bichitra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703992/
https://www.ncbi.nlm.nih.gov/pubmed/26738801
http://dx.doi.org/10.1038/srep18880