Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

β-Lactams are the most successful antibacterials, but their effectiveness is threatened by resistance, most importantly by production of serine- and metallo-β-lactamases (MBLs). MBLs are of increasing concern because they catalyze the hydrolysis of almost all β-lactam antibiotics, including recent-g...

Descripción completa

Detalles Bibliográficos
Autores principales: Brem, Jürgen, van Berkel, Sander S., Zollman, David, Lee, Sook Y., Gileadi, Opher, McHugh, Peter J., Walsh, Timothy R., McDonough, Michael A., Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704194/
https://www.ncbi.nlm.nih.gov/pubmed/26482303
http://dx.doi.org/10.1128/AAC.01335-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704194/
https://www.ncbi.nlm.nih.gov/pubmed/26482303
http://dx.doi.org/10.1128/AAC.01335-15

Ejemplares similares