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CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial

BACKGROUND: Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by a transcriptional autoregulatory feedback loop involving core clock genes. CLOC...

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Detalles Bibliográficos
Autores principales: Corella, Dolores, Asensio, Eva. M., Coltell, Oscar, Sorlí, José V., Estruch, Ramón, Martínez-González, Miguel Ángel, Salas-Salvadó, Jordi, Castañer, Olga, Arós, Fernando, Lapetra, José, Serra-Majem, Lluís, Gómez-Gracia, Enrique, Ortega-Azorín, Carolina, Fiol, Miquel, Espino, Javier Díez, Díaz-López, Andrés, Fitó, Montserrat, Ros, Emilio, Ordovás, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704407/
https://www.ncbi.nlm.nih.gov/pubmed/26739996
http://dx.doi.org/10.1186/s12933-015-0327-8