An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function

BACKGROUND: In genome-wide association studies (GWAS) for complex diseases, the association between a SNP and each phenotype is usually weak. Combining multiple related phenotypic traits can increase the power of gene search and thus is a practically important area that requires methodology work. Th...

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Detalles Bibliográficos
Autores principales: Yang, James J., Li, Jia, Williams, L. Keoki, Buu, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704475/
https://www.ncbi.nlm.nih.gov/pubmed/26729364
http://dx.doi.org/10.1186/s12859-015-0868-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704475/
https://www.ncbi.nlm.nih.gov/pubmed/26729364
http://dx.doi.org/10.1186/s12859-015-0868-6

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