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An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function
BACKGROUND: In genome-wide association studies (GWAS) for complex diseases, the association between a SNP and each phenotype is usually weak. Combining multiple related phenotypic traits can increase the power of gene search and thus is a practically important area that requires methodology work. Th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704475/ https://www.ncbi.nlm.nih.gov/pubmed/26729364 http://dx.doi.org/10.1186/s12859-015-0868-6 |