A Tandem Oligonucleotide Approach for SNP-Selective RNA Degradation Using Modified Antisense Oligonucleotides

Antisense oligonucleotides have been studied for many years as a tool for gene silencing. One of the most difficult cases of selective RNA silencing involves the alleles of single nucleotide polymorphisms, in which the allele sequence is differentiated by a single nucleotide. A new approach to impro...

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Detalles Bibliográficos
Autores principales: Magner, Dorota, Biala, Ewa, Lisowiec-Wachnicka, Jolanta, Kierzek, Elzbieta, Kierzek, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704561/
https://www.ncbi.nlm.nih.gov/pubmed/26544037
http://dx.doi.org/10.1371/journal.pone.0142139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704561/
https://www.ncbi.nlm.nih.gov/pubmed/26544037
http://dx.doi.org/10.1371/journal.pone.0142139

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