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CYP2D6 copy number distribution in the US population

The cytochrome P450 2D6 (CYP2D6) gene is perhaps the most well characterized gene involved in drug metabolism and is known to have both gene duplication and deletion variants that are inheritable and stable. In a set of over 30 000 deidentified clinical samples we found that 12.6% of all patients te...

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Detalles Bibliográficos
Autores principales: Beoris, Michelle, Amos Wilson, Jean, Garces, Jorge A., Lukowiak, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704658/
https://www.ncbi.nlm.nih.gov/pubmed/26551314
http://dx.doi.org/10.1097/FPC.0000000000000188