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CYP2D6 copy number distribution in the US population
The cytochrome P450 2D6 (CYP2D6) gene is perhaps the most well characterized gene involved in drug metabolism and is known to have both gene duplication and deletion variants that are inheritable and stable. In a set of over 30 000 deidentified clinical samples we found that 12.6% of all patients te...
Autores principales: | Beoris, Michelle, Amos Wilson, Jean, Garces, Jorge A., Lukowiak, Andrew A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704658/ https://www.ncbi.nlm.nih.gov/pubmed/26551314 http://dx.doi.org/10.1097/FPC.0000000000000188 |
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