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Identification of a Classical Mutant in the Industrial Host Aspergillus niger by Systems Genetics: LaeA Is Required for Citric Acid Production and Regulates the Formation of Some Secondary Metabolites

The asexual filamentous fungus Aspergillus niger is an important industrial cell factory for citric acid production. In this study, we genetically characterized a UV-generated A. niger mutant that was originally isolated as a nonacidifying mutant, which is a desirable trait for industrial enzyme pro...

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Detalles Bibliográficos
Autores principales: Niu, Jing, Arentshorst, Mark, Nair, P. Deepa S., Dai, Ziyu, Baker, Scott E., Frisvad, Jens C., Nielsen, Kristian F., Punt, Peter J., Ram, Arthur F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704718/
https://www.ncbi.nlm.nih.gov/pubmed/26566947
http://dx.doi.org/10.1534/g3.115.024067