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Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-Trait Mapping

We previously proposed a simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. In order to better handle the case of noisy phenotype measurements and accommodate the correlation structure among time points, we propose an alternative approach that mainta...

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Detalles Bibliográficos
Autores principales: Kwak, Il-Youp, Moore, Candace R., Spalding, Edgar P., Broman, Karl W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704727/
https://www.ncbi.nlm.nih.gov/pubmed/26530421
http://dx.doi.org/10.1534/g3.115.024133