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The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages

L. pneumophila is the causative agent of Legionnaires’ disease, a human illness characterized by severe pneumonia. In contrast to those derived from humans, macrophages derived from most mouse strains restrict L. pneumophila replication. The restriction of L. pneumophila replication has been shown t...

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Detalles Bibliográficos
Autores principales: Abu Khweek, Arwa, Kanneganti, Apurva, C. Guttridge D, Denis, Amer, Amal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704736/
https://www.ncbi.nlm.nih.gov/pubmed/26741365
http://dx.doi.org/10.1371/journal.pone.0146410