Faster Adaptation in Smaller Populations: Counterintuitive Evolution of HIV during Childhood Infection

Analysis of HIV-1 gene sequences sampled longitudinally from infected individuals can reveal the evolutionary dynamics that underlie associations between disease outcome and viral genetic diversity and divergence. Here we extend a statistical framework to estimate rates of viral molecular adaptation...

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Detalles Bibliográficos
Autores principales: Raghwani, Jayna, Bhatt, Samir, Pybus, Oliver G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704780/
https://www.ncbi.nlm.nih.gov/pubmed/26741359
http://dx.doi.org/10.1371/journal.pcbi.1004694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704780/
https://www.ncbi.nlm.nih.gov/pubmed/26741359
http://dx.doi.org/10.1371/journal.pcbi.1004694

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