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Development of Biomarkers Based on DNA Methylation in the NCAPH2/LMF2 Promoter Region for Diagnosis of Alzheimer’s Disease and Amnesic Mild Cognitive Impairment

From the standpoint of early interventions for dementia, a convenient method of diagnosis using biomarkers is required for Alzheimer’s disease (AD) in the early stage as well as amnesic mild cognitive impairment (aMCI). Focusing on differences in DNA methylation due to AD and aMCI, in the present st...

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Detalles Bibliográficos
Autores principales: Kobayashi, Nobuyuki, Shinagawa, Shunichiro, Nagata, Tomoyuki, Shimada, Kazuya, Shibata, Nobuto, Ohnuma, Tohru, Kasanuki, Koji, Arai, Heii, Yamada, Hisashi, Nakayama, Kazuhiko, Kondo, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704831/
https://www.ncbi.nlm.nih.gov/pubmed/26742120
http://dx.doi.org/10.1371/journal.pone.0146449